Abca7 CLIA Kit for Mouse(Mus musculus) | EIAab.comAbca7 CLIA Kit for Mouse(Mus musculus)

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Abca7 (Gene name),

ATP-binding cassette sub-family A member 7 (Protein name ), ABCA7_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Abca7;

Protein name:

ATP-binding cassette sub-family A member 7;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.

Subcellular Location:

Cell membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Endosome membrane Multi-pass membrane protein Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.

Protein Attributes:

Sequence length:

2159

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2159:

DPSSVETMI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q91V24

Pfam:

PF00005

String:

Q91V24

UniGene:

Mm.103351

KEGG:

mmu:27403

Uniprot:

Q91V24

FOR

ELISA Kit for Mouse ATP-binding cassette sub-family A member 7

Cat.:

E15004h

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Packing:

96T

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ELISA Kit for Mouse ATP-binding cassette sub-family A member 7

Cat.:

E15004m

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Mouse ATP-binding cassette sub-family A member 7

MSDS:

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CLIA Kit for Mouse ATP-binding cassette sub-family A member 7

MSDS:

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CLIA Kit for Mouse ATP-binding cassette sub-family A member 7

Cat.:

U15004h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse ATP-binding cassette sub-family A member 7

Cat.:

U15004m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse ATP-binding cassette sub-family A member 7

Monoclonal Antibody for Mouse ATP-binding cassette sub-family A member 7

Protein for Mouse ATP-binding cassette sub-family A member 7

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter."
Broccardo C. , Osorio J. , Luciani M.-F. , Schriml L.M. , Prades C. , Shulenin S. , Arnould I. , Naudin L. , Lafargue C. , Rosier M. , Jordan B. , Mattei M.-G. , Dean M. , Denefle P. , Chimini G.
Cytogenet. Cell Genet.92:264-270(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: DBA/2.
tissue: Lymphoma.
2.

"Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus."
Schriml L.M. , Dean M.
Genomics64:24-31(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1920-2159
strain: C57BL/6J.
3.

"ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux."
Wang N. , Lan D. , Gerbod-Giannone M. , Linsel-Nitschke P. , Jehle A.W. , Chen W. , Martinez L.O. , Tall A.R.
J. Biol. Chem.278:42906-42912(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
4.

"Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver."
Wakaumi M. , Ishibashi K. , Ando H. , Kasanuki H. , Tsuruoka S.
Clin. Exp. Pharmacol. Physiol.32:1034-1041(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
5.

"Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels."
Kim W.S. , Fitzgerald M.L. , Kang K. , Okuhira K. , Bell S.A. , Manning J.J. , Koehn S.L. , Lu N. , Moore K.J. , Freeman M.W.
J. Biol. Chem.280:3989-3995(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
6.

"ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages."
Jehle A.W. , Gardai S.J. , Li S. , Linsel-Nitschke P. , Morimoto K. , Janssen W.J. , Vandivier R.W. , Wang N. , Greenberg S. , Dale B.M. , Qin C. , Henson P.M. , Tall A.R.
J. Cell Biol.174:547-556(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE
7.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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